Symbol
Name
ID

Gimap5
GTPase, IMAP family member 5
MGI:2442232

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

abnormal B cell proliferation

decreased B cell proliferation

thymus atrophy

decreased thymocyte number

abnormal common myeloid progenitor cell morphology

abnormal erythropoiesis

abnormal CD8-positive, alpha-beta T cell differentiation

extramedullary hematopoiesis

anemia

abnormal bone marrow cell morphology/development

abnormal common lymphocyte progenitor cell morphology

abnormal erythrocyte morphology

abnormal erythrocyte cell number

decreased hematocrit

abnormal hemoglobin content

decreased hemoglobin content

increased red blood cell distribution width

anisocytosis

increased neutrophil cell number

increased granulocyte number

thrombocytopenia

abnormal lymphocyte cell number

decreased mature B cell number

decreased B-1 B cell number

decreased B cell number

decreased NK cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased NK T cell number

decreased T cell number

decreased lymphocyte cell number

increased hematopoietic stem cell number

abnormal leukocyte morphology

abnormal spleen morphology

spleen hypoplasia

abnormal spleen B cell follicle morphology

decreased spleen B cell follicle number

decreased spleen B cell follicle size

abnormal B cell physiology

decreased IgG1 level

decreased IgG2a level

decreased IgG2b level

decreased IgG3 level

decreased IgG level

decreased IgM level

abnormal NK T cell physiology

Availability

Mouse Genotype

Gimap3^tm1.1Yout/Gimap3^tm1.1Yout

Gimap5^m1Btlr/Gimap5^m1Btlr

Gimap5^tm1Wlr/Gimap5^tm1Wlr

Gimap5^tm1Yout/Gimap5^tm1Yout

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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